Case report: Coexistence of Labbe vein thrombosis and autoimmune encephalitis with two different antibodies

Anti-NMDA receptor encephalitis is an autoimmune well- known to pediatric neurologists. The characteristic combination of symptoms and detection NMDA antibody can confirm the diagnosis. Most children respond well immunosuppressive therapy. Anti-GABAB usually occurs in adult patients. patients present clinically with limbic encephalitis. Cases are rare. Cerebral venous thrombosis also has a very low incidence without underlying diseases. Patients headaches, convulsions, focal deficits. Anticoagulants first choice treatment. We report boy initially diagnosed Labbe vein later tested positive for both GABAB receptors. did not relieve boy's symptoms, therapy achieved good results. titers were significantly reduced or even turned negative. Although was recanalized at four months follow-up, brain lesion absorbed. learn from this case that child be inflicted cerebral simultaneously. Child